Antimicrobial Resistance in Hospital-acquired Bloodstream Infections among Children in a Pediatric Hospital in Bolivia

J Glob Infect Dis. 2025 Mar 31;17(1):10-16. doi: 10.4103/jgid.jgid_130_24. eCollection 2025 Jan-Mar.ABSTRACTINTRODUCTION: Antimicrobial resistance (AMR) is a growing threat to global public health. In hospitals, infant mortality due to bacterial sepsis is associated with AMR. The epidemiology of AMR

D Diana Rodriguez

Hospital-wide, dynamic, individualized prediction of central line-associated bloodstream infections-development and temporal evaluation of six prediction models

BMC Infect Dis. 2025 Apr 24;25(1):597. doi: 10.1186/s12879-025-10854-1.ABSTRACTBACKGROUND: Central line-associated bloodstream infections (CLABSI) are preventable hospital-acquired infections. Predicting CLABSI helps improve early intervention strategies and enhance patient safety.AIM: To develop an

E Elena Albu

Developing a User-Centric System for Hospital-Onset Bacteremia Risk Assessment and Visualization: An Integrated Requirements Analysis Approach

Stud Health Technol Inform. 2025 Apr 24;324:51-56. doi: 10.3233/SHTI250160.ABSTRACTBACKGROUND: Hospital-onset bacteremia (HOB) is one of the most common hospital-acquired infections, resulting in increased in-hospital morbidity and mortality. To support clinicians in assessing patients at risk, data

A Anna Thalea Hoogestraat

The NOSTRA model: Coherent estimation of infection sources in the case of possible nosocomial transmission

PLoS Comput Biol. 2025 Apr 21;21(4):e1012949. doi: 10.1371/journal.pcbi.1012949. Online ahead of print.ABSTRACTNosocomial, or hospital-acquired, infections are a key determinant of patient health in healthcare facilities, leading to longer stays and increased mortality. In addition to the direct eff

D David J Pascall

Use of Antibiotics and Severe Bacterial Infections Within the First 6 Months of Life-A Population-Based Cohort Study From East Denmark

Acta Paediatr. 2025 Apr 21. doi: 10.1111/apa.70103. Online ahead of print.ABSTRACTAIM: To investigate antibiotic exposure and the incidence of severe bacterial infections during the first 6 months of life in preterm infants born between 28 and 37 weeks of gestation.METHODS: Retrospective population-

A Anna Bjerager Arnesen

Risk for development of vancomycin resistant enterococci bacteremia among colonized or infected patients, a multiple center, retrospective study in Palestine

Sci Rep. 2025 Apr 16;15(1):13182. doi: 10.1038/s41598-025-93956-9.ABSTRACTVancomycin-Resistant Enterococcus (VRE) is one of the key antibiotic-resistant pathogens that challenges the health system with its threat to human health. Most VRE infections occur in hospital settings as these pathogens are

D Dana Sadaqa

Practice guideline on the prevention and treatment of central line associated bloodstream infection in 2025

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2025 Mar;37(3):193-220. doi: 10.3760/cma.j.cn121430-20250301-00199.ABSTRACTCentral line associated bloodstream infection (CLABSI) is the most severe complication of indwelling intravascular catheters and one of the most common causes of intensive care unit (ICU

N None Chinese Society Of Critical Care Medicine

Serratia marcescens and its role in Pink breast milk and upper GI bleeding in an infant: a Tanzanian case report

BMC Infect Dis. 2025 Apr 8;25(1):482. doi: 10.1186/s12879-025-10862-1.ABSTRACTBACKGROUND: Serratia marcescens, a gram-negative bacterium once considered non-pathogenic, is now recognized as a cause of hospital-acquired infections, particularly in immunocompromised patients with outbreaks reported in

R Rukhsar Osman

Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database

Intensive Care Med. 2025 Mar;51(3):518-528. doi: 10.1007/s00134-025-07857-6. Epub 2025 Apr 7.ABSTRACTINTRODUCTION: Hospital-acquired bloodstream infections (HA-BSIs) are severe and require antibiotic therapy. In non-complicated BSIs, shortened therapy reduces side effects without compromising effica

L Lena Gajdos

Mineralized Bacteria as a Potent Vaccine Against Staphylococcus aureus Infections

Small. 2025 Apr 3:e2412279. doi: 10.1002/smll.202412279. Online ahead of print.ABSTRACTStaphylococcus aureus (S. aureus) as common Gram-positive pathogenic bacteria, causes local and systemic infections, including sepsis and bacteremia. In particular, the high prevalence of drug-resistant S. aureus

X Xiaojing Chen

Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia

Pneumologie. 2025 Apr 1. doi: 10.1055/a-2541-9872. Online ahead of print.ABSTRACTBACKGROUND: Nosocomial pneumonia, encompassing hospital-acquired (HAP) and ventilator-associated pneumonia (VAP), remains a major cause of morbidity and mortality in hospitalized adults. In response to evolving pathoge

J Jessica Rademacher

Antimicrobial Activity of the Peptide C14R Against Ab Initio Growing and Preformed Biofilms of Candida albicans, Candida parapsilosis and Candidozyma auris

Biomolecules. 2025 Feb 21;15(3):322. doi: 10.3390/biom15030322.ABSTRACTBiofilms are the predominant lifeforms of microorganisms, contributing to over 80% of infections, including those caused by Candida species like C. albicans, C. parapsilosis and Candidozyma auris. These species form biofilms on m

J Jan-Christoph Walter

Real-World Use, Effectiveness, and Safety of Intravenous Fosfomycin: The FORTRESS Study

Infect Dis Ther. 2025 Apr;14(4):765-791. doi: 10.1007/s40121-025-01125-2. Epub 2025 Mar 19.ABSTRACTINTRODUCTION: Intravenous fosfomycin (FOS) is a broad-spectrum antibiotic primarily used in combination therapy to treat severe infections caused by both Gram-positive (GP) and Gram-negative (GN) patho

K Klaus-Friedrich Bodmann

Epidemiological analysis of intra-abdominal infections in Italy from the Italian register of complicated intra-abdominal infections-the IRIS study: a prospective observational nationwide study

World J Emerg Surg. 2025 Mar 17;20(1):22. doi: 10.1186/s13017-025-00590-x.ABSTRACTBACKGROUND: Intra-abdominal infections (IAIs) are common and severe surgical emergencies associated with high morbidity and mortality. In recent years, there has been a worldwide increase in antimicrobial resistance as

F Federico Coccolini

Bacteraemia in a Nigerian hospital: Implementing antimicrobial resistance surveillance

J Public Health Afr. 2025 Feb 7;16(1):655. doi: 10.4102/jphia.v16i1.655. eCollection 2025.ABSTRACTBACKGROUND: Surveillance of drug-resistant infections is crucial for antimicrobial resistance (AMR) control. Implementing surveillance in low- and middle-income countries (LMICs) is challenging.AIM: To

A Adewale A Amupitan

Central line-associated bloodstream infections (CLABSI) in pediatric and neonatal intensive care units-The VINCat program 2013-2022

Enferm Infecc Microbiol Clin (Engl Ed). 2025 Mar 12:S2529-993X(25)00058-9. doi: 10.1016/j.eimce.2024.09.014. Online ahead of print.ABSTRACTINTRODUCTION: Central line-associated bloodstream infections (CLABSI) are among the most common and preventable hospital-acquired infections in pediatric and neo

M Mireia Urrea Ayala

Pediatric Gram-negative bloodstream infections: epidemiology, antibiotic resistance, clinical outcomes and factors affecting mortality, a single center retrospective study

J Infect Dev Ctries. 2025 Feb 28;19(2):238-247. doi: 10.3855/jidc.20258.ABSTRACTINTRODUCTION: The increasing prevalence of Gram-negative bloodstream infections in pediatric patients poses significant treatment challenges, particularly from multi-drug resistant (MDR) strains. Despite advances in medi

S Seyhan Yilmaz

Adherence to standard infection prevention and control practices and factors associated among healthcare workers at Juba Teaching Hospital, Juba-South Sudan: a cross-sectional study

J Health Popul Nutr. 2025 Mar 6;44(1):66. doi: 10.1186/s41043-025-00807-4.ABSTRACTBACKGROUND: Hospital-acquired infections, including COVID-19 and sepsis, pose a significant threat to healthcare workers' productivity and patients' safety globally. Adhering to standard infection prevention and contro

C Chubang Augustine Khamsa

Neon Pink Breast Milk Stain in the NICU

Cureus. 2025 Feb 3;17(2):e78425. doi: 10.7759/cureus.78425. eCollection 2025 Feb.ABSTRACTPink discoloration in breast milk is a rare phenomenon arising from various benign or pathological causes. Serratia marcescens, a gram-negative bacterium known for its characteristic red pigment prodigiosin, is

B Brenda Stanley

Current trends in the epidemiology of multidrug-resistant and beta-lactamase-producing Pseudomonas aeruginosa in Asia and Africa: a systematic review and meta-analysis

PeerJ. 2025 Feb 24;13:e18986. doi: 10.7717/peerj.18986. eCollection 2025.ABSTRACTPseudomonas aeruginosa continues to be a significant contributor to high morbidity and mortality rates worldwide, particularly due to its role in severe infections such as hospital-acquired conditions, including ventila

M Mohd Zulkifli Salleh

Utilising routinely collected clinical data through time series deep learning to improve identification of bacterial bloodstream infections: a retrospective cohort study

Lancet Digit Health. 2025 Mar;7(3):e205-e215. doi: 10.1016/j.landig.2025.01.010.ABSTRACTBACKGROUND: Blood cultures are the gold standard for diagnosing bacterial bloodstream infections, but test results are only available 24-48 h after sampling. We aimed to develop and evaluate models using health-c

D Damien K Ming

"Unmasking the Uncommon": A case series of multi-drug resistant Elizabethkingia meningoseptica causing late-onset sepsis and meningitis in preterm neonates

F1000Res. 2025 Feb 6;13:1367. doi: 10.12688/f1000research.158137.2. eCollection 2024.ABSTRACTElizabethkingia meningoseptica is an uncommon nosocomial pathogen that causes meningitis, pneumonia, and sepsis in neonates and in immunocompromised individuals. It exhibits resistance to many commonly emplo

P Prajnha U P

Which antimicrobial treatment for patients with bloodstream infection during ECMO support?

Eur J Clin Microbiol Infect Dis. 2025 Apr;44(4):905-914. doi: 10.1007/s10096-025-05059-y. Epub 2025 Feb 8.ABSTRACTOJECTIVE: We aim to describe a large, multicenter cohort of patients with bloodstream infection (BSI) acquired during extracorporeal membrane oxygenation (ECMO) support.METHODS: We condu

N Nicolas Massart

Identification of circulating Tfh/Th subsets as a biomarker of developed hospital-acquired pneumonia

Front Immunol. 2025 Jan 22;16:1513939. doi: 10.3389/fimmu.2025.1513939. eCollection 2025.ABSTRACTBACKGROUND: This study aimed to explore the possible value of follicular helper T (Tfh) cells in hospital-acquired pneumonia (HAP).METHODS: Flow cytometry was used to measure circulating Tfh and helper T

Y Yuan Peng