A battery-free nanofluidic intracellular delivery patch for internal organs

The targeted delivery of therapeutics to internal organs to, for example, promote healing or apoptosis holds promise in the treatment of numerous diseases^(1-4). Currently, the prevailing delivery modality relies on the circulation; however, this modality has substantial efficiency, safety and/or co

D Dedong Yin

Association between the body mass index and risk of cardiovascular events in sodium-glucose cotransporter 2 inhibitor users compared with dipeptidyl-peptidase 4 inhibitor users: A nationwide cohort study in Korea

Diabetes Obes Metab. 2025 Apr 28. doi: 10.1111/dom.16416. Online ahead of print.ABSTRACTAIMS: There is limited evidence regarding whether obesity modifies the association between the use of sodium-glucose cotransporter 2 inhibitors (SGLT2is) and the risk of cardiovascular events. We assessed whether

H Hwa Yeon Ko

Voice Assessment and Vocal Biomarkers in Heart Failure: A Systematic Review

Circ Heart Fail. 2025 Apr 24:e012303. doi: 10.1161/CIRCHEARTFAILURE.124.012303. Online ahead of print.ABSTRACTDespite major advances in recent years, the timely detection and prevention of incipient congestion in patients with chronic heart failure remains challenging. Most approaches are either inv

M Maximilian Bauser

Human de novo mutation rates from a four-generation pedigree reference

Understanding the human de novo mutation (DNM) rate requires complete sequence information¹. Here using five complementary short-read and long-read sequencing technologies, we phased and assembled more than 95% of each diploid human genome in a four-generation, twenty-eight-member family (CEPH 1463)

D David Porubsky

Dissecting the Genetic Architecture of Intracranial Aneurysms

Circ Genom Precis Med. 2025 Apr 21:e004626. doi: 10.1161/CIRCGEN.123.004626. Online ahead of print.ABSTRACTBACKGROUND: The genetic risk of intracranial aneurysm (IA) development has been ascribed to the genetic risk of smoking exposure and hypertension. The relationship of IA to other cardiovascular

S Shaunak S Adkar