J Pak Med Assoc. 2025 Apr;75(4):662-666. doi: 10.47391/JPMA.25-30.
ABSTRACT
Electrolyte imbalances are a common and challenging aspect of managing chronic kidney disease (CKD). Despite advances in treatment, a phenomenon known as "electrolyte inertia"- the inertness to correcting abnormal electrolyte levels- may persist in CKD patients. This inertia can result from various factors which include delayed therapeutic intervention, the complexity of multiple coexisting comorbidities, and the judicious balanced therapeutic approach necessitated by the multidyselectrolytaemia in CKD management. Through the concept of "electrolyte inertia," we explore the underlying causes for this phenomenon, its clinical implications, and strategies to overcome it, to achieve better patient care in CKD.
PMID:40269383 | DOI:10.47391/JPMA.25-30