Breast Cancer Res. 2025 May 1;27(1):67. doi: 10.1186/s13058-025-02031-8.ABSTRACTBACKGROUND: Incidence of premenopausal breast cancer (BC) has risen in recent years, though most existing BC prediction models are not generalizable to young women due to underrepresentation of this age group in model de
Syst Rev. 2025 May 1;14(1):98. doi: 10.1186/s13643-025-02858-4.ABSTRACTBACKGROUND AND AIM: In recent years, endocan has emerged as a potential biomarker in various medical conditions. This multifaceted molecule, involved in key processes such as inflammation and endothelial dysfunction, has shown pr
BMC Gastroenterol. 2025 May 1;25(1):327. doi: 10.1186/s12876-025-03924-w.ABSTRACTBACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is recognized as the predominant chronic liver disorder globally. Inflammation is integral to the onset and progression of NAFLD. The C-reactive protein to lymphocyt
BMC Public Health. 2025 May 1;25(1):1619. doi: 10.1186/s12889-025-22743-y.ABSTRACTBACKGROUND: Loneliness is prevalent in patients with chronic diseases and can threaten their health status, treatment process and quality of life. The stigma of loneliness stems from a derogatory and stigmatizing label
BMC Musculoskelet Disord. 2025 May 1;26(1):437. doi: 10.1186/s12891-025-08701-0.ABSTRACTBACKGROUND: Degeneration of the intervertebral disc is a significant source of chronic axial low back pain. Direct supplementation of degenerated nucleus pulposis (NP) tissue with intradiscally delivered allogene
Sci Rep. 2025 May 1;15(1):15273. doi: 10.1038/s41598-025-99831-x.ABSTRACTPreterm infants born in the saccular stage of lung development are at risk for developing bronchopulmonary dysplasia (BPD). Oxygen toxicity and volutrauma are identified as major contributors of BPD. Despite mitigation of these
Sci Rep. 2025 May 1;15(1):15309. doi: 10.1038/s41598-025-98991-0.ABSTRACTInflammatory bowel disease (IBD) is an autoimmune disease (AD) characterized by chronic, relapsing intestinal inflammation. Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement and ove
Sci Rep. 2025 May 1;15(1):15277. doi: 10.1038/s41598-025-99891-z.ABSTRACTAccording to the WHO and domestic statistics, chronic diseases are one of the most common causes of disability in the Polish society, as well as in the world. The presence of the disease significantly reduces the quality of lif
Sci Rep. 2025 May 1;15(1):15293. doi: 10.1038/s41598-025-92247-7.ABSTRACTKnee osteoarthritis (OA) and atopic diseases are both characterized by chronic inflammation, yet their potential relationship remains unexplored. This study investigates whether atopic diseases are associated with an increased
Sci Rep. 2025 May 1;15(1):15283. doi: 10.1038/s41598-025-00291-0.ABSTRACTHandgrip strength is a key indicator of overall health in older adults, and its decline is linked to various adverse health outcomes. Despite numerous studies on factors influencing handgrip strength, few attempts have integrat
BMC Public Health. 2025 May 1;25(1):1603. doi: 10.1186/s12889-025-22828-8.ABSTRACTINTRODUCTION: Chronic kidney disease is defined by the presence of kidney damage or decreased kidney function for at least three months, irrespective of the cause. Hypertensive kidney disease is one of the long-term co
BMC Pediatr. 2025 May 1;25(1):345. doi: 10.1186/s12887-025-05632-6.ABSTRACTINTRODUCTION: T1 Diabetes (T1D) is one of the most common chronic diseases in children and young people [1] with almost 34 000 aged 18 years or less living with T1D [2]. Physical activity is promoted as one of a number of man
BMC Gastroenterol. 2025 May 1;25(1):325. doi: 10.1186/s12876-025-03915-x.ABSTRACTBACKGROUND: Metabolic dysfunction-associated fatty liver disease (MAFLD) has become the most prevalent chronic liver condition in adolescents. The triglyceride-glucose (TyG) index, a surrogate marker of insulin resistan
J Geriatr Psychiatry Neurol. 2025 May 1:8919887251339837. doi: 10.1177/08919887251339837. Online ahead of print.ABSTRACTBackgroundSubjective memory complaints (SMC) are common in older adults and may indicate an increased risk of cognitive decline. Polypharmacy and anticholinergic burden have been a
J Appl Toxicol. 2025 May 1. doi: 10.1002/jat.4802. Online ahead of print.ABSTRACTBeryllium and its compounds are classified as carcinogens, and prolonged exposure can trigger chronic beryllium disease. The Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling is known to
Transplant Proc. 2025 Apr 30:S0041-1345(25)00234-9. doi: 10.1016/j.transproceed.2025.04.009. Online ahead of print.ABSTRACTWe present the outcomes of organ recipients from a 69-year-old female donor diagnosed with occult breast cancer. The donor had no relevant medical history nor aberrant finding o
Cardiovasc Revasc Med. 2025 Apr 17:S1553-8389(25)00176-9. doi: 10.1016/j.carrev.2025.04.025. Online ahead of print.ABSTRACTChronic coronary syndromes (CCS) include 2 overlapping subgroups of patients - those with angina with nonobstructive coronary arteries (ANOCA), or ischaemia with non-obstructive
Lancet Digit Health. 2025 Apr 30:100868. doi: 10.1016/j.landig.2025.02.008. Online ahead of print.ABSTRACTBACKGROUND: Improving the accessibility of screening diabetic kidney disease (DKD) and differentiating isolated diabetic nephropathy from non-diabetic kidney disease (NDKD) are two major challen
J Rheumatol. 2025 May 1:jrheum.2024-1218. doi: 10.3899/jrheum.2024-1218. Online ahead of print.ABSTRACTOBJECTIVE: Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are chronic immune-mediated inflammatory diseases often complicated by persistent pain and fatigue despite cutting edge p
J Acad Consult Liaison Psychiatry. 2025 Apr 29:S2667-2960(25)00478-1. doi: 10.1016/j.jaclp.2025.04.003. Online ahead of print.ABSTRACTBACKGROUND: Anticipatory grief (AG) is a common experience that affects caregivers of patients with chronic illnesses, particularly Alzheimer's disease. Cognitive dis
Clin Nutr ESPEN. 2025 Apr 29:S2405-4577(25)00286-4. doi: 10.1016/j.clnesp.2025.04.024. Online ahead of print.ABSTRACTBACKGROUND: The Dietary Inflammatory Index (DII), a novel tool for quantifying the inflammatory potential of one's diet, has been extensively employed in various chronic disease resea
Pract Radiat Oncol. 2025 Apr 29:S1879-8500(25)00108-0. doi: 10.1016/j.prro.2025.03.014. Online ahead of print.ABSTRACTPURPOSE: Regional nodal irradiation (RNI) is increasingly utilized in place of axillary lymph node dissection (ALND) in carefully selected breast cancer patients. While hypofractione
Curr Probl Cardiol. 2025 Apr 29:103070. doi: 10.1016/j.cpcardiol.2025.103070. Online ahead of print.ABSTRACTINTRODUCTION: Testosterone therapy may improve physical capacity and mood in men with chronic heart failure. However, recent findings have raised concerns that testosterone therapy could also
Autoimmun Rev. 2025 Apr 29:103825. doi: 10.1016/j.autrev.2025.103825. Online ahead of print.ABSTRACTMultiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS), characterized by demyelination, neuroinflammation, and the progressive accumulation of neurologic deficits
